protease$64750$ - définition. Qu'est-ce que protease$64750$
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Qu'est-ce (qui) est protease$64750$ - définition

CLASS OF ANTIVIRAL DRUGS USED TO TREAT HIV/AIDS AND HEPATITIS C
Protease inhibitors; Hiv protease inhibitors; HIV protease inhibitor; Pharmacologic protease inhibitor; Protease Inhibitors; HIV protease inhibitors; HCV protease inhibitor
  • The number of people in the U.S. dying of HIV fell by 60% in the 2 years following the introduction of the first HIV protease inhibitors

Variably protease-sensitive prionopathy         
HUMAN DISEASE
Protease-sensitive prionopathy; VPSPr; VPSPR; Variably protease sensitive prionopathy
Variably protease-sensitive prionopathy (VPSPr) (formerly known as Protease Sensitive Prionopathy) is a sporadic prion protein disease first described in an abstract for a conference on prions in 2006, and this study was published in a 2008 report on 11 cases. The study was conducted by Gambetti P.
Protease inhibitor (pharmacology)         
Protease inhibitors (PIs) are medications that act by interfering with enzymes that cleave proteins. Some of the most well known are antiviral drugs widely used to treat HIV/AIDS and hepatitis C.
Intramembrane protease         
Intramembrane-cleaving protease; Regulated intramembrane proteolysis
Intramembrane proteases (IMPs), also known as intramembrane-cleaving proteases (I-CLiPs), are enzymes that have the property of cleaving transmembrane domains of integral membrane proteins. All known intramembrane proteases are themselves integral membrane proteins with multiple transmembrane domains, and they have their active sites buried within the lipid bilayer of cellular membranes.

Wikipédia

Protease inhibitor (pharmacology)

Protease inhibitors (PIs) are medications that act by interfering with enzymes that cleave proteins. Some of the most well known are antiviral drugs widely used to treat HIV/AIDS hepatitis C and COVID-19. These protease inhibitors prevent viral replication by selectively binding to viral proteases (e.g. HIV-1 protease) and blocking proteolytic cleavage of protein precursors that are necessary for the production of infectious viral particles.

Protease inhibitors that have been developed and are currently used in clinical practice include:

Given the specificity of the target of these drugs there is the risk, like with antibiotics, of the development of drug-resistant mutated viruses. To reduce this risk, it is common to use several different drugs together that are each aimed at different targets.